Artificial Intelligence for Onco-Plasma

IA4OP is a 3 year project (2020-2023) funded by the plan Cancer via the INSERM-MIC program.

The objective of this project is to create a universal and non-invasive method to help diagnose cancers. The proposed method is based on the existence of unique plasma denaturation profiles (signatures) for different cancers. The plasma denaturation profile represents the total denaturation curve (under the influence of temperature) of its constituent proteins.

In the context of the project presented, we plan to demonstrate : (1) that nanoDSF can unambiguously distinguish several cancers using developed machine learning methods from a simple plasma sample; (2) that the new nanoDSF instrument (Tycho) is as sensitive as the research oriented Prometheus NT.Plex for determining plasma denaturation profiles as an aid to diagnosis.

If this sounds interesting to you, please check the dedicated website!